Aged Garlic Extract Benefits

February 7, 2016
Aged Garlic Extract Benefits

Researchers and nutritionists have always hailed garlic for its health benefits. Most of the health benefits of garlic are due to its high antioxidant content. You might not agree with the strong taste and pungent odor of garlic, but what you can’t disagree with is the treasure of health benefits garlic holds.

How good would that be if you could reap all the benefits of garlic and don’t smell awkward at the same time? That would be great, right? Here is great news for you! The health benefits of garlic are actually not linked to its freshness. In fact, researchers have found that the S-allylcysteine – the most potent and abundant antioxidant in garlic- content is highest in Aged Garlic Extract (AGE) 1)http://jn.nutrition.org/content/131/3/955S.short.


It means AGE is the best way of using garlic without having to worry about its socially deterring odor! Let’s dig deep into this centuries-old magic ingredient and see what science says about aged garlic extract benefits.

Constituents of Aged Garlic Extract (AGE)

Aged Garlic Extract-capsules
Fresh garlic is rich in antioxidants too, but these are two main issues with those antioxidants. First, most of the antioxidants are rather unstable and break down into less effective products when you consume them. Second, the bioavailability of these antioxidants is quite poor.

Aging takes away the unpleasant odor and smell of garlic but blesses it with antioxidants. Aging slowly breaks down the unstable antioxidant fractions into more stable and potent versions. AGE is extremely rich in potent antioxidants like S-allylmercaptocysteine (SAMC) and S-allylcysteine (SAC) 2)http://www.ncbi.nlm.nih.gov/pubmed/9306260?dopt=Abstract 3)http://www.ncbi.nlm.nih.gov/pubmed/7997468?dopt=Abstract.
Another reason why most antioxidant rich foods, like fresh garlic and red grapes, don’t work is that their antioxidants are not readily bioavailable. This means, the antioxidants you get into your systems, get flushed out into your toilet without even getting absorbed from your gut. But, AGE has an upper hand here too! The bioavailability of AGE can be as high as 98% 4)http://www.ncbi.nlm.nih.gov/pubmed/8073085?dopt=Abstract.

Oxidative Stress and Your Health

The terms like ‘oxidative stress’, ‘reactive oxygen species’ and ‘body toxins’ get used a lot these days. That’s because our understanding of oxidative stress and its impacts on our health has covered huge leaps in the last few years. It has traveled from a concept of Sci-Fi to the realm of living.
Now we know that oxidative stress is the basic culprit behind countless health issues like cardiovascular disease like heart attack and high blood pressure 5)http://www.ncbi.nlm.nih.gov/pubmed/10872549. In addition, it has got an important role in the progression of ischemic brain diseases 6)http://www.ncbi.nlm.nih.gov/pubmed/9989455 and age-related disorders like Alzheimer’s disease 7)http://www.ncbi.nlm.nih.gov/pubmed/10681270. Oxidative stress specifically targets your immune system, making it weak and ineffective 8)http://www.ncbi.nlm.nih.gov/pubmed/22542123. Above all, its role has been implicated in the progression of different cancerous conditions 9)http://www.ncbi.nlm.nih.gov/pubmed/20840865.

Aged Garlic Extract Benefits (AGE)

garlic-extract-capsules
The bad news is that you’re continuously exposed to oxidative stress. It gets into your body systems through the chemicals, pollutants, toxins, drugs and hormones from the food you eat and air you breathe. That’s why you need protection from these tiny boogers that are destroying your health from within. Call AGE to your rescue! How AGE achieves this feat? What are the several health benefits of AGE? Let’s dig in!

AGE protects your heart

Cholesterol- mainly the low-density lipoprotein (LDL) variety of cholesterol- is implicated in cardiovascular diseases and high blood pressure. LDL is harmful to your health on its own. But when it reacts with oxidative stress, it becomes more toxic and sticks to the vessels to occlude them. The end result is increased chances of heart attack and hypertension 10)http://pharmrev.aspetjournals.org/content/48/1/3.abstract?ijkey=a18f0ff915a6d4a8d1fce2a92c69db06acc5924f&keytype2=tf_ipsecsha 11)http://www.ncbi.nlm.nih.gov/pubmed/9306260?dopt=Abstract. Once the walls of blood vessels are damaged, the blood clotting cells (platelets) start to stick to them. These changes further speed up the progression of heart disease 12)http://www.ncbi.nlm.nih.gov/pubmed/14622657.
If your doctor has told you to keep your cholesterol level under control, then AGE is the best thing you can try! AGE inhibits- and rather reverses- all the processes that lead to poor heart health. It lowers the level of LDL and inhibits its oxidation 13)http://www.ncbi.nlm.nih.gov/pubmed/9247357?dopt=Abstract. Moreover, it reduces platelet aggregation and forming of atherosclerotic plaque -a plug of cholesterol that blocks your blood vessels 14)http://www.hindawi.com/journals/omcl/2012/907162/.

AGE lowers blood pressure

Aged Garlic Extract
High blood pressure, or hypertension, is a silent killer as it slowly dements almost all of your body systems. You could use drugs to cope with a problem, but using drugs have issues of its own. Drugs cause a lot of undesirable side effects too and cost a little more than natural methods. But, that doesn’t have to be like this anymore!

Researchers have found that AGE is an effective way to treat high blood pressure. A Randomized Control Trial (RCT) tested the effects of AGE on 79 hypertensive individuals. Only after 12 weeks of use, the participants experienced as much as 15 mmHg reduction in their blood pressure. In addition, none of the participants reported any undesirable side effects after the use of AGE 15)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561616/. Researchers concluded that blood pressure lowering effects of AGE are mainly due to its ability to relax blood vessels, reduce oxidative stress and inhibit the chemical processes that cause hypertension 16)http://www.ncbi.nlm.nih.gov/pubmed/16484561/ 17)http://www.ncbi.nlm.nih.gov/pubmed/17951430/ 18)http://www.ncbi.nlm.nih.gov/pubmed/19904760/.

AGE is neuroprotective

smoked-garlic
Your brain is the most complex yet the most sensitive organ in your body. The effects of oxidative stress are most pronounced on your brain. Oxidative insult results in increased risk of brain ischemia (stroke), degenerative disorders like Alzheimer’s, Huntington’s disease and many more 19)http://dx.doi.org/10.1016/S0028-3908%2801%2900019-3.

AGE comes to the rescue of the brain in several different ways.

AGE protects your brain from oxidative damage and significantly decreases the chances of brain ischemia 20)http://www.sciencedirect.com/science/article/pii/0197018695001174. Not only that, but it might actually reverse the damage done to the brain due to any type of injury! Results of a research showed that AGE was able to increase the survival rate of brain neurons (brain cells) when exposed to insult and it was able to increase the neuronal branching- an indication of better neuronal function 21)http://onlinelibrary.wiley.com/doi/10.1002/%28SICI%291099-1573%28199609%2910:6%3C468::AID-PTR877%3E3.0.CO;2-I/abstract.

AGE is a novel cure from Alzheimer’s disease

Alzheimer’s is an age-related disorder that affects millions of Americans. Researchers have recently found that oxidative stress and inflammation are the main culprits for causing this condition 22)http://www.sciencedirect.com/science/article/pii/S0891584996006296. These features cause damage to the brain cells. Once brain cells are dead, your brain starts to shrink and you develop symptoms of Alzheimer’s like forgetfulness and inability to do even routine tasks.


Research shows that AGE is highly potent in reducing the oxidative stress responsible for this condition 23)http://www.medscimonit.com/abstract/index/idArt/13593/act/2 24)http://www.sciencedirect.com/science/article/pii/S0168010203000373. In addition, it also puts a stop to other changes in the brain related to this condition 25)http://jneuroinflammation.biomedcentral.com/articles/10.1186/1742-2094-6-41. Finally, use of AGE is also responsible for retarding the accelerated death of neurons, which is the major pathology in Alzheimer’s disease 26)http://www.sciencedirect.com/science/article/pii/S0006899303031731 27)http://www.sciencedirect.com/science/article/pii/S0306452203006390.

AGE keeps you young for longer

garlic-on-table
Believe it or not, AGE is centuries old fountain of youth. If you want to look young and stay young then AGE is the thing you need in life! Researchers have now discovered that oxidative stress is to blame for the normal (or abnormal) aging process 28)dx.doi.org/10.1016/j.freeradbiomed.2011.05.039. Oxidative stress causes premature death of body cells, which translates as signs of aging like wrinkling of skin, hair loss, loss of skin glossiness and so on. Researchers found that use of AGE effectively slows down aging29)https://www.jstage.jst.go.jp/article/bpb1993/17/12/17_12_1589/_article 30)http://onlinelibrary.wiley.com/doi/10.1111/j.1440-1681.1997.tb01813.x/abstract. So if you want to live a youthful life for long, then AGE should be on the top of list for you!

AGE boosts immune function

Your immune system is your main line of defense against foreign invaders like bacteria, viruses, toxins, chemicals and drugs. The immune system consists of two main components: the immune cells and immune chemicals. These limbs of immune system work together and protect you against invading entities.

As mentioned before, oxidative stress is responsible for deterioration of normal immune responses. This means, increased oxidative stress makes you more vulnerable to viral, bacterial and fungal infections. You can stop that with one simple thing. That one simple thing is aged garlic extract!

Japanese researchers found that AGE was able to strengthen both limbs of immune system i.e. immune cells and immune chemicals 31)http://www.ncbi.nlm.nih.gov/pubmed/11238820. In another study 32)http://www.ncbi.nlm.nih.gov/pubmed/22280901, researchers at the University of Florida tested AGE for its ability to strengthen the immune system and protect the participants of the study against viral flu and cold. The participants were asked to consume AGE. Researchers made some remarkable discoveries!

They found that AGE was able to reduce the incidence of cold by a staggering 60%. Moreover, it was also able to reduce the severity of symptoms by 61%!

If there is a viral, bacterial or fungal infection ailing you, you can use AGE to boost your immune function and protect your body from these sticky invaders.

AGE offers protection against cancer

garlic-image

Like all the conditions mentioned so far, cancer is the most lethal manifestation of increased oxidative stress in your body. Researchers have now increasingly started to recognize high oxidative stress as the main culprit for different cancers 33)http://www.ncbi.nlm.nih.gov/pubmed/19149749. Oxidative stress damages the DNA of your body cells. Cells with abnormal DNA start to divide aberrantly and the final result is cancer development.

There are a number of ways AGE protect you against oxidative stress-induced cancer. First, it prevents the metabolism of cancer-causing chemicals and stops them from turning into their active states 34)jn.nutrition.org/cgi/ijlink?linkType=ABST&journalCode=carcin&resid=14/8/1627.

Second, AGE is extremely rich in selenium. Selenium is an important mineral and an important part of your antioxidant body system. It has the ability to considerably reduce oxidative stress responsible for cancer development 35)jn.nutrition.org/cgi/ijlink?linkType=ABST&journalCode=pnas&resid=83/5/1490.

Third, not only it prevents cancer development, but also stops the spreading of cancer once it develops. Allixin – another important antioxidant constituent of AGE- is responsible for putting a stop to the process of cancer progression and spreading 36)http://jn.nutrition.org/content/131/3/1010S.long.

We’re still learning a lot about this amazing natural wonder, but having it in your routine could be a good idea if you’re worried about cancer.

It detoxifies the liver

Liver is the primary site of your body where all the toxins and drugs are metabolized, detoxified and excreted. But, there is a limit to which liver can perform this function. Once that limit is reached, these toxins start to inflict irreparable damage to your liver. In such conditions, you can use AGE as it helps the liver in its detoxifying action, by reducing the level of toxins in your body 37)http://www.sciencedirect.com/science/article/pii/S0300483X98000183 38)http://www.ncbi.nlm.nih.gov/pubmed/1903884?dopt=Abstract. This way, it protects your liver from damage.

There you have it. These are some of the countless health benefits of aged garlic extract. This amazing ingredient can transform your life in a natural way!

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References   [ + ]

1.http://jn.nutrition.org/content/131/3/955S.short
2, 11.http://www.ncbi.nlm.nih.gov/pubmed/9306260?dopt=Abstract
3.http://www.ncbi.nlm.nih.gov/pubmed/7997468?dopt=Abstract
4.http://www.ncbi.nlm.nih.gov/pubmed/8073085?dopt=Abstract
5.http://www.ncbi.nlm.nih.gov/pubmed/10872549
6.http://www.ncbi.nlm.nih.gov/pubmed/9989455
7.http://www.ncbi.nlm.nih.gov/pubmed/10681270
8.http://www.ncbi.nlm.nih.gov/pubmed/22542123
9.http://www.ncbi.nlm.nih.gov/pubmed/20840865
10.http://pharmrev.aspetjournals.org/content/48/1/3.abstract?ijkey=a18f0ff915a6d4a8d1fce2a92c69db06acc5924f&keytype2=tf_ipsecsha
12.http://www.ncbi.nlm.nih.gov/pubmed/14622657
13.http://www.ncbi.nlm.nih.gov/pubmed/9247357?dopt=Abstract
14.http://www.hindawi.com/journals/omcl/2012/907162/
15.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561616/
16.http://www.ncbi.nlm.nih.gov/pubmed/16484561/
17.http://www.ncbi.nlm.nih.gov/pubmed/17951430/
18.http://www.ncbi.nlm.nih.gov/pubmed/19904760/
19.http://dx.doi.org/10.1016/S0028-3908%2801%2900019-3
20.http://www.sciencedirect.com/science/article/pii/0197018695001174
21.http://onlinelibrary.wiley.com/doi/10.1002/%28SICI%291099-1573%28199609%2910:6%3C468::AID-PTR877%3E3.0.CO;2-I/abstract
22.http://www.sciencedirect.com/science/article/pii/S0891584996006296
23.http://www.medscimonit.com/abstract/index/idArt/13593/act/2
24.http://www.sciencedirect.com/science/article/pii/S0168010203000373
25.http://jneuroinflammation.biomedcentral.com/articles/10.1186/1742-2094-6-41
26.http://www.sciencedirect.com/science/article/pii/S0006899303031731
27.http://www.sciencedirect.com/science/article/pii/S0306452203006390
28.dx.doi.org/10.1016/j.freeradbiomed.2011.05.039
29.https://www.jstage.jst.go.jp/article/bpb1993/17/12/17_12_1589/_article
30.http://onlinelibrary.wiley.com/doi/10.1111/j.1440-1681.1997.tb01813.x/abstract
31.http://www.ncbi.nlm.nih.gov/pubmed/11238820
32.http://www.ncbi.nlm.nih.gov/pubmed/22280901
33.http://www.ncbi.nlm.nih.gov/pubmed/19149749
34.jn.nutrition.org/cgi/ijlink?linkType=ABST&journalCode=carcin&resid=14/8/1627
35.jn.nutrition.org/cgi/ijlink?linkType=ABST&journalCode=pnas&resid=83/5/1490
36.http://jn.nutrition.org/content/131/3/1010S.long
37.http://www.sciencedirect.com/science/article/pii/S0300483X98000183
38.http://www.ncbi.nlm.nih.gov/pubmed/1903884?dopt=Abstract